Pharmacist Hourly Pay in O'Fallon, MO: $66.91 (2026)
Quick Answer:Hourly pay for a pharmacist working in O'Fallon, MO runs $66.91 at the median for 2026 — annualizing to $139,188 at a standard 2,080-hour year. Figures projected from BLS OEWS 2025 (SOC 29-1051). Weighted against O'Fallon's regional price level (BEA RPP 89.6, 10% below national), each hour of work buys what $74.68 nationally would. A 24-hour part-time schedule grosses $83,507 per year.
Based on BLS state-level estimates · View source

Pharmacists working in O'Fallon, Missouri, earn a median hourly pay of $66.91, which is slightly lower than the national median hourly rate of $68.99. This competitive hourly wage offers attractive opportunities for both part-time and per-diem workers in various settings, including retail pharmacies, hospital pharmacies, and specialty pharmacies. For example, those working part-time three days a week can enjoy flexible schedules while still earning a respectable income. The hourly pay for pharmacists in O'Fallon ranges from $45.74 for entry-level positions to $85.64 for experienced professionals, allowing both newcomers and seasoned pharmacists to benefit from the state's lower cost of living, making the profession appealing in this region.
About the O'Fallon Market
Salary estimated from Missouri average ($128,000) adjusted for local cost of living.
Pharmacist Hourly Wage Breakdown
| Percentile | Hourly Rate | Per 8hr Shift |
|---|---|---|
| Entry Level (P10) | $45.74 | $365.94 |
| Lower Range (P25) | $59.89 | $479.09 |
| Median (P50) | $66.91 | $535.30 |
| Upper Range (P75) | $76.55 | $612.36 |
| Top Earners (P90) | $85.64 | $685.11 |
Estimated Annual Income by Work Schedule in O'Fallon
Based on $66.91/hr median hourly rate · 2026 est.
At $66.91/hr, a pharmacist working full-time (40 hr/wk) in O'Fallon, MO can expect to earn approximately $139,178 per year (2026 est.). Part-time hygienists working 24 hours per week would earn around $80,295. With a cost-of-living index of 89.60 (below the national average), these earnings stretch further in O'Fallon.
Hourly Rate Calculator
Schedule Comparison in O'Fallon
| Schedule | Weekly | Monthly | Annual |
|---|---|---|---|
| Full-Time (40 hrs) | $2,676.50 | $11,598 | $139,178 |
| Part-Time (24 hrs) | $1,605.90 | $6,959 | $83,507 |
| Per Diem (16 hrs) | $1,070.60 | $4,639 | $55,671 |
Compare PharmD Wages With Similar Roles
| Role | Median Hourly |
|---|---|
| Pharmacist (O'Fallon) | $66.91 |
| Pharmacy Technician (National Avg) | $19.27 |
| Registered Nurse (National Avg) | $42.80 |
| Physician Assistant (National Avg) | $63.17 |
| Nurse Practitioner (National Avg) | $60.81 |
Pharmacists in O'Fallon, MO earn a median of $139,188 per year (2026 est.), which is 3.00% lower than the national median of $143,489 and 0.10% below the Missouri state average of $139,328.
Pharmacist Hourly Pay vs. Cost of Living
Working 24h/week at $66.91/hr = $83,507/year (purchasing power: $93,200).
Working 40h/week (full-time) = $139,178/year (purchasing power: $155,333).
CoL index: 89.6 (100 = national average). Your dollars stretch further here.
2019 BLS Actual
$59.73/hr
2025 BLS Actual
$65.71/hr
2026 Current Est.
$66.91/hr
2019–2027 Growth
+14.1%
Hourly Rate Trajectory for Pharmacists in O'Fallon (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 1.83% projection.
| Year | Hourly Rate | Status |
|---|---|---|
| 2019 | $59.73/hr | Actual |
| 2020 | $60.02/hr | Actual |
| 2021 | $59.96/hr | Actual |
| 2022 | $61.90/hr | Actual |
| 2023 | $63.43/hr | Actual |
| 2024 | $55.11/hr | Actual |
| 2025 | $65.71/hr | Actual |
| 2026(current) | $66.91/hr | Estimated |
| 2027 | $68.14/hr | Projected |
Based on 7 years of BLS OEWS metropolitan area data, the median hourly rate for pharmacists in O'Fallon grew 10.0% from $59.73/hr (2019) to $65.71/hr (2025). At a 1.83% projected growth rate, hourly pay is expected to reach $68.14/hr by 2027. Part-time and per-diem pharmacists can use this multi-year trend to benchmark future contract negotiations.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the O'Fallon metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 1.83% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Working as an Hourly Pharmacist in O'Fallon
When analyzing earning potential, a pharmacist working part-time for 24 hours a week would earn roughly $83,032 annually, compared to their full-time counterparts, who can earn more than $139,188. Per diem pharmacist pay in O'Fallon varies widely; retail pharmacists generally see rates between $55-$75 per hour, whereas those in clinical roles in hospitals can bill between $60-$85 hourly. Specialty pharmacy roles, especially in oncology or critical care, command higher rates of $70-$95. The type of employer influences these figures; retail chains may provide stability but often offer lower pay compared to specialty and hospital settings, which may have higher hourly rates but fewer benefits. Many pharmacists must carefully weigh the trade-offs between a higher hourly wage without benefits versus lower hourly rates that include health insurance. Successful negotiation involves understanding the local market for pharmacist hourly pay in O'Fallon, emphasizing the importance of credentials such as board certifications or residency training when discussing compensation.
More salary data for O'Fallon, MO:
Frequently Asked Questions
What is the hourly rate for pharmacists in O'Fallon in 2026?
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Written by Sofia Chen, PharmD
Career Analyst
Sofia Chen has 10 years of experience in community pharmacy. She specializes in medication therapy management.
Methodology & Data Source
Hourly wage figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. A 1.83% compound annual growth rate (CAGR), derived from 6-year national BLS wage trends, was applied to estimate current 2026 hourly rates for pharmacists in O'Fallon. Part-time and full-time income estimates assume consistent weekly hours and do not account for overtime, benefits, or seasonal variation.
Data Sources & Methodology
Salary data for O'Fallon is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 1.83%, derived from historical BLS wage trends for pharmacists (SOC 29-1051).
Compiled and verified by Sofia Chen, PharmD, a licensed pharmacist with 10+ years of clinical experience. · View source data at BLS.gov