O'Fallon vs St. Louis: Pharmacist Salary (2026)
Compare pharmacist salaries between O'Fallon, MO and St. Louis, MO. All figures are 2026 estimates projected from BLS 2025 data.
Side-by-Side Comparison
| Metric | O'Fallon, MO | St. Louis, MO |
|---|---|---|
| Median Salary | $139,188 | $141,065▲ |
| Hourly Rate | $66.91 | $67.82▲ |
| Entry Level (P10) | $95,146 | $113,143▲ |
| 25th Percentile | $124,558 | $132,135▲ |
| 75th Percentile | $159,214 | $162,551▲ |
| Top Earner (P90) | $178,125▲ | $169,893 |
| Total Employed | 22 | 2,910▲ |
Verdict
St. Louis, MO offers better overall compensation for pharmacists, winning 3 out of 4 metrics compared to O'Fallon.
The salary gap between O'Fallon and St. Louis is $1,877 (1.35%). St. Louis's median is -1.69% compared to the US national median of $143,489.
Salary Range Comparison
The full salary range (10th to 90th percentile) in O'Fallon spans $82,979,St. Louis spans $56,750. O'Fallon has a wider pay range, meaning more potential for high earners but also more variation.
Cost-of-Living Adjusted Comparison
After cost-of-living adjustment, O'Fallon ($155,344 effective) pays 4.71% more than St. Louis ($148,352 effective).
Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.
Which City Is Right for You?
Choose O'Fallon if…
- ✓Better top-earner potential ($178,125)
- ✓Better purchasing power (CoL-adjusted: $155,344)
- ✓You prefer the Missouri area and lifestyle
Choose St. Louis if…
- ✓Higher median salary ($141,065/year)
- ✓Larger job market (2,910 employed)
- ✓You prefer the Missouri area and lifestyle
Historical Salary Growth Comparison
Based on BLS OEWS metropolitan area data, pharmacist salaries in O'Fallon grew 19.2% from 2024 to 2025, compared to 9.0% growth in St. Louis over the same period.
O'Fallon, MO
$114,627 (2024) → $136,687 (2025)
St. Louis, MO
$127,060 (2019) → $138,530 (2025)
View Full Salary Data
O'Fallon, MO
St. Louis, MO
Frequently Asked Questions
Which city pays pharmacists more: O'Fallon or St. Louis?
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Related Comparisons
Written by Sofia Chen, PharmD
Career Analyst
Sofia Chen has 10 years of experience in community pharmacy. She specializes in medication therapy management.
Methodology & Data Source
All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 1.83% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.
Data Sources & Methodology
Source: BLS, OEWS , released .
Compiled and verified by Sofia Chen, PharmD, a licensed pharmacist with 10+ years of clinical experience. · View source data at BLS.gov