Pharmacist Salary

San Francisco vs San Jose: Pharmacist Salary (2026)

Compare pharmacist salaries between San Francisco, CA and San Jose, CA. All figures are 2026 estimates projected from BLS 2025 data.

San Francisco, CA
$180,657
$86.85/hr
San Jose, CA
$202,682
$97.44/hr

Side-by-Side Comparison

MetricSan Francisco, CASan Jose, CA
Median Salary$180,657$202,682
Hourly Rate$86.85$97.44
Entry Level (P10)$138,061$154,680
25th Percentile$167,571$161,177
75th Percentile$224,148$228,944
Top Earner (P90)$233,415$238,364
Total Employed3,6701,960
Side-by-side bar chart comparing San Francisco ($180,657) and San Jose ($202,682) pharmacist salaries.San FranciscoSan JoseMedian Salary$180,657$202,682Entry Level (P10)$138,061$154,680Top Earner (P90)$233,415$238,364US Median $143,489

Verdict

San Jose, CA offers better overall compensation for pharmacists, winning 3 out of 4 metrics compared to San Francisco.

The salary gap between San Francisco and San Jose is $22,025 (12.19%). San Jose's median is +41.25% compared to the US national median of $143,489.

Salary Range Comparison

The full salary range (10th to 90th percentile) in San Francisco spans $95,354,San Jose spans $83,684. San Francisco has a wider pay range, meaning more potential for high earners but also more variation.

San Francisco
P10 (Entry)$138,061
P25$167,571
Median$180,657
P75$224,148
P90 (Top)$233,415
San Jose
P10 (Entry)$154,680
P25$161,177
Median$202,682
P75$228,944
P90 (Top)$238,364

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Jose ($183,551 effective) pays 17.46% more than San Francisco ($156,260 effective).

San Francisco
Nominal: $180,657
CoL Index: 115.613
Adjusted: $156,260
San Jose
Nominal: $202,682
CoL Index: 110.423
Adjusted: $183,551

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose San Francisco if…

  • Larger job market (3,670 employed)
  • You prefer the California area and lifestyle

Choose San Jose if…

  • Higher median salary ($202,682/year)
  • Better top-earner potential ($238,364)
  • Better purchasing power (CoL-adjusted: $183,551)
  • You prefer the California area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, pharmacist salaries in San Francisco grew 15.3% from 2019 to 2025, compared to 27.6% growth in San Jose over the same period.

San Francisco, CA

+15.3%

$153,870 (2019) → $177,410 (2025)

San Jose, CA

+27.6%

$155,970 (2019) → $199,040 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays pharmacists more: San Francisco or San Jose?

San Jose has a higher median pharmacist salary at $202,682/year, compared to San Francisco at $180,657/year — a difference of $22,025 (12.19%).

What is the hourly rate difference between San Francisco and San Jose?

San Francisco pharmacists earn $86.85/hr while San Jose hygienists earn $97.44/hr (2026 est.).

Should I relocate from San Francisco to San Jose as a pharmacist?

Consider more than just salary when comparing San Francisco and San Jose. Factor in cost of living (CoL-adjusted: San Francisco = $156,260, San Jose = $183,551), job availability (3,670 vs 1,960 employed), commute, and career growth potential.

What do entry-level pharmacists earn in San Francisco vs San Jose?

Entry-level (10th percentile) pharmacists earn $138,061 in San Francisco and $154,680 in San Jose. The San Jose area offers higher starting salaries.

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Written by Sofia Chen, PharmD

Career Analyst

Sofia Chen has 10 years of experience in community pharmacy. She specializes in medication therapy management.

Clinically reviewed by Liam Patel, PharmDData verified by Amina Al-Sayed, PharmD

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 1.83% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Sofia Chen, PharmD, a licensed pharmacist with 10+ years of clinical experience. · View source data at BLS.gov